Unit 5: Infectious Diseases Pharmacology

Unit 5: Infectious Diseases Pharmacology

A significant aspect of primary care involves the management of infectious diseases. You will encounter antibiotics, antivirals, and antifungals—agents with which you need to become highly acquainted and develop a strong knowledge base and application skills. Invest time in studying these modules and seek supplementary resources to enhance your understanding. Some of these resources are listed in the optional books section of the syllabus. Categorizing these agents into classes and understanding their mechanisms of action can greatly facilitate comprehension. When prescribing anti-infective agents, consider factors such as sensitivity and resistance. Additionally, there are steps in the selection of antimicrobial drugs to contemplate once a diagnosis or differential diagnosis is established. It becomes apparent that an accurate diagnosis or differential diagnosis is pivotal for rational drug selection. Furthermore, special population characteristics must be taken into account.

Unit Learning Objectives
1. Explore the principles of pathophysiology and therapeutics guiding pharmacotherapeutic interventions for infectious diseases.
2. Analyze the pharmacokinetic and pharmacodynamic actions of agents employed in the management of infectious diseases.
3. Apply evidence-based pharmacotherapeutic interventions for patients with infectious diseases.
4. Apply critical-thinking processes to manage and evaluate the expected effects and potential adverse effects of pharmacodynamic agents.

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Week 7/Unit 5 “To Do” List
– Complete High-Yield Med Review Infectious Disease Quiz by Sunday of Week 7
– Shadow Health Focused Exam: Pediatric GAS Pharyngitis due Sunday of Week 7
– Shadow Health Anti-infectives Concept Lab due Sunday of Week 7
– Prepare for Unit 4 & 5 Exam next week!

Learning Materials

Learning Materials
Lectures & E-Book
Busti, A. J. (2022). NP Curriculum Support-Advanced Pharmacology for NPs. MedEducation, LLC.
INFECTIOUS DISEASES PHARMACOLOGY
– Penicillin Agents
– Cephalosporins
– Fosfomycin
– Macrolides
– Fluoroquinolones
– Antibiotics-other
– Anaerobic Agents
– Influenza-Antiviral Review
– Antifungals
SPECIAL TOPICS IN PHARMACOLOGY
– Drug Allergies and Cross Reactivity – Penicillin Allergies
– Drug Allergies and Cross Reactivity – Sulfa Allergies
ADVANCED DRUG CLASS REVIEW TOPICS
– Ophthalmic Antibiotics for Bacterial Eye Infections

Optional Learning Resources:
Media
Khan Academy Medicine. (2015, June 26). Treating HIV: Antiretroviral drugs, infectious disease [Video]. YouTube. https://www.youtube.com/watch?v=GR9d9wrOl5E
Parkes, C. (2019, June 26). Nursing pharmacology – TB, antiprotozoal, antifungal and antiviral meds [Video]. YouTube. https://www.youtube.com/watch?v=gEcQrLpdi1I
Speed Pharmacology. (2018, March 26). Pharmacology – antibiotic – cell wall and membrane inhibitors (made easy) [Video]. YouTube. https://www.youtube.com/watch?v=mMk6VWVpRpo
Speed Pharmacology. (2018, May 3). Pharmacology – antibiotics – DNA, RNA, folic acids, protein synthesis inhibitors [Video]. YouTube. https://www.youtube.com/watch?v=5HQmvQJWzNY

Websites
Gilbert, D. N., Chambers, H. F., Eliopoulos, G. M., Saag, M.S., & Pavia. A. T. (2017). The Sanford guide to antimicrobial therapy (47th ed.). Sperryville, VA: Antimicrobial Therapy.
Note: This resource is also available in electronic book formats and mobile formats at https://store.sanfordguide.com/antimicrobial-therapy-c2.aspx
Hollier, A. (2011). Pediatric dosage cards. Lafayette, LA: Advanced Practice Education Associates.
Note: These dosage cards can be purchased at https://www.apea.com/clinical-resources/pediatric-dosage-cards
Khan Academy. (2018n). Infectious diseases. Retrieved March 11, 2021, https://www.khanacademy.org/science/health-and-medicine/infectious-diseases

HYMR Quiz – Infectious Disease
Following review of all assigned lectures and correlating E-book chapters in High Yield Med Review, you will complete the module quiz in the HYMR platform.
– From the Dashboard select “EXAMS”
– Navigate to the “Infectious Diseases – Self Assessment”
– Click “Take Exam”
You will have one attempt to complete 10 questions in 15 minutes. Once completed, please take a screen shot of your score and upload it to this assignment tab for grading. This quiz is worth 20 points, so based on your % score you will receive the correlating points below.
– 100% 20 points
– 90% 18 points
– 80% 16 points
– 70% 14 points
– 60% 12 points
– 50% 10 points
– 40% 8 points
– 30% 6 points
– 20% 4 points
– 10% 2 points
– No submission 0 points
*Please note, faculty are able to view your time and activity in HYMR.*

Shadow Health: Concept Lab – Anti-infectives
The purpose of this Shadow Health Concept Lab assignment is to help you achieve the following Course Learning Outcomes 1-5.
Assignment:
This week you will participate in a Shadow Health Concept Lab pertaining to anti-infective medications. This will allow you to learn about pharmacological concepts related to commonly administered anti-infective drugs. This module should take approximately 30 minutes to complete.
What to Submit:
Upon completion of the assignment:
– Submit your completion certificate
– Submit your reflection response to the questions below
Reflection Response Instructions: Submit a 1 page reflection response to the questions below. Please use APA format and include one scholarly reference.
– What are some available resources/guidelines that you will use to help select appropriate antibiotics? Give a brief overview of how this will apply to your NP practice.

Shadow Health Technical Support
If at any time you have any questions or encounter any technical issues regarding the Digital Clinical Experience, please contact the Shadow Health support specialists by visiting the Learner Support Page at http://support.shadowhealth.com for contact information and hours. You may email the Learner Support team directly at support@shadowhealth.com at any time or by calling 800.860.3241.

Shadow Health: Focused Exam: Pediatric GAS Pharyngitis
The purpose of this Shadow Health Focused Exam assignment is to help you achieve Course Learning Outcomes 1-5.
Assignment:
This assignment provides the opportunity to conduct a focused exam on a pediatric patient who presents with Group A Streptococcal Pharyngitis. You will interview Sophia Haddad and her father, Omar, using therapeutic communication and obtain enough subjective data to determine the appropriate

pharmacological therapy for her condition. After the patient exam, you will select the most appropriate medication for Ms. Haddad and educate her father on how to safely administer it and care for Sophia while she is sick. If applicable, you will write a prescription for the selected medication.

NRNP/PRAC 6635 Comprehensive Psychiatric Evaluation Template Example

What to Submit:
Upon completion of the assignment, submit your completion certificate/lab pass that shows the DCE score to this assignment link..

Shadow Health Grading
All assignments will be graded using the DCE Score. Reopening and multiple attempts are allowed so the student can submit the best score for grading. Each student will submit the “lab pass” showing their DCE score to the designated assignment tab in Blackboard. Grading will be based on the DCE score received on the assignment that correlates with the points allocated in the table below. An incomplete assignment will result in the grade of zero. Faculty will monitor student engagement within the Shadow Health platform to ensure active participation to complete all the assignment requirements.
DCE Score
– 95-100 20
– 90-94 18
– 85-89 15
– 80-84 13
– Below 79 10
– No submission 0
Login page: “Shadow Health Access” link on left panel
Assignment Due Date: Sunday of Week 6

Shadow Health Technical Support
If at any time you have any questions or encounter any technical issues regarding the Digital Clinical Experience, please contact the Shadow Health support specialists by visiting the Learner Support Page at http://support.shadowhealth.com for contact information and hours. You may email the Learner Support team directly at support@shadowhealth.com at any time or by calling 800.860.3241.

Unit Conclusion

Unit Conclusion
As we conclude week 7 of Advanced Pharmacology, we have covered a substantial amount of information related to a common area of primary care, which involves the treatment of infectious diseases. I encourage you to continue investing time in studying this material and seek additional resources to support your success. As you further integrate this knowledge, you will appreciate the critical role of an accurate diagnosis or differential diagnosis in rational drug selection.