NUR7560900 – Advanced Pharmacology

Unit 1: Foundations of Pharmacology

Welcome to the Advanced Pharmacology course. During the first week, we will establish the essential foundation for understanding the principles of pharmacology, the role of pharmacology in healthcare, and considerations related to different patient populations. Effective drug selection requires a deep understanding of the scope of practice, ethical considerations, and legal issues. This week, we will also explore relatively new areas in pharmacotherapy, such as pharmacogenomics and ethnopharmacology, which help identify the most suitable drugs for specific populations. This knowledge will build upon your undergraduate foundation and provide you with the perspective of a prescriber, emphasizing clinical judgment in prescribing and collaboration with other healthcare providers. Throughout this course, you will delve into the pharmacodynamics, pharmacokinetics, and pharmacotherapeutics of common drugs used for various body systems and medical conditions.

Unit 1 Learning Objectives
1. Establish a foundation of knowledge and an inquisitive attitude to effectively and safely prescribe pharmacotherapeutic interventions for patients (CLO 1).
2. Utilize resources to monitor pharmacodynamic, pharmacokinetic, and pharmacotherapeutic interactions, optimizing patient outcomes while minimizing adverse effects (CLO 2).
3. Apply pharmacogenetics in practice (CLO 4).
4. Identify legal and ethical issues in prescribing (CLO 1).
5. Understand the process of prescription writing (CLO 1, 4).

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Unit 1 (Week 1 & 2) “To Do” List
– Review the course syllabus/course schedule, including due dates and course flow.
– Obtain access to High-Yield Med Reviews (HYMR) for course lectures and the e-book.
– Complete the Unit 1 HYMR reading and lecture requirements.
– Familiarize yourself with Shadow Health.
– Register your account in Shadow Health.
– Complete Shadow Health Orientation and Conversation Concept Lab.
– Begin the State Practice Discussion with your initial post due by the end of Week 1 and your peer post due by the end of Week 2.
– Review CDC Module 1 and take the quiz.
– Complete the Respondus Practice Quiz (Note: You will need to download the Respondus browser first).

NRNP-6645 Mother and Daughter a Cultural Tale Video Family Assessment Assignment NRNP/PRAC 6645 Comprehensive Psychiatric

NUR 7560 Course Orientation

Learning Materials

Lecture & E-Book
Busti, A. J. (2022). NP Curriculum Support-Advanced Pharmacology for NPs. MedEducation, LLC.
FOUNDATIONS OF PHARMACOLOGY
– Pharmacokinetics Part 1
– Pharmacokinetics Part 2
– Pharmacokinetics Part 3
– Pharmacogenetics in Practice
– Drug Interactions
– Special Populations
– Prescription Writing
– Prescription Template

Link 2: A helpful 60-second video on how to write a prescription for PMHNPs.

Supplemental Material (Optional):
Media
Agency for Healthcare Research and Quality. CHAIN ONLINE: Clinical consumer health advisory information network.
Medicocurio. Pharmacogenomics: Genes and medicine [Video].
RS TU. Pharmacoeconomics [Video].
Epocrates is a valuable app or desktop resource for prescribing and managing medications.
CredibleMeds provides medication safety tools and resources.
Monthly Prescribing Reference offers up-to-date drug safety information and clinical charts.
U.S. FDA Website provides comprehensive information on various topics.

Shadow Health

The purpose of Shadow Health assignments is to use clinical simulation technology to enhance your understanding of advanced pharmacology concepts. These assignments align with the following course learning outcomes (CLOs):
CLO 1: Apply critical thinking and best scientific evidence to manage and evaluate expected effects, potential adverse effects, and potential interactions of pharmacological agents for the treatment of self-limiting acute conditions and chronic diseases across the lifespan.
CLO 2: Analyze the pharmacodynamics and pharmacokinetic impact of pharmacologic therapies in the treatment of diseases and altered states.
CLO 3: Formulate therapeutic regimens for patients, including special populations, using cultural competence.
CLO 4: Evaluate the impact of pharmacogenomics, access, cost, quality, and safety on prescribing.
CLO 5: Examine the significance of interprofessional collaboration on patient outcomes.

Assignment: View the Shadow Health orientation video.
Assignment: Complete the Shadow Health Conversation Concepts Lab.

Faculty Lecture: Chapter 1 – The Role of the Advance Practice Nurse Practitioner as Prescriber

Unit 1 Discussion

This discussion allows you to demonstrate the following course learning outcomes (CLOs):
CLO 1: Apply critical thinking and best scientific evidence to manage and evaluate expected effects, potential adverse effects, and potential interactions of pharmacological agents for the treatment of self-limiting acute conditions and chronic diseases across the lifespan.
CLO 4: Evaluate the impact of pharmacogenomics, access, cost, quality, and safety on prescribing.

After reviewing Unit 1 and learning materials, please address the following questions:

1. In your state, is physician collaboration required for nurse practitioners to practice independently, or can nurse practitioners practice independently? Are there any practice restrictions for nurse practitioners in your state?

2. Does nurse practitioner practice in your state require collaboration for prescribing, or can nurse practitioners independently prescribe medications? Are there any prescription restrictions, such as controlled substances limitations, in your state?

3. Share your stance on whether nurse practitioners should require collaboration for practice and prescribing. Support your viewpoint with scholarly, evidence-based information.

4. Does your state have a Prescription Drug Monitoring Program (PDMP) or Controlled Substance Utilization Review and Evaluation System (CURES) system? If so, provide details about this system, such as the timeline for prescription uploads and reporting. Explain how this system will impact your future FNP practice.

Please follow these guidelines for your initial and peer posts:
– Include at least 2 scholarly, peer-reviewed sources published within the last 5 years in your

response.
– Use a professional format with appropriate APA citations and references.
– Respond to at least 2 peers whose state of practice differs from your own. Include at least 1 scholarly, peer-reviewed source published within the last 5 years in your response.

CDC Module Training

To prepare for your future practice and management of patient pain, it is essential to understand the significance of prescribing opioids. This assignment aligns with the following course learning outcomes (CLOs):
CLO 1: Apply critical thinking and best scientific evidence to the management and evaluation of expected effects, potential adverse effects, and potential interactions of pharmacological agents for the treatment of self-limiting acute conditions and chronic diseases across the lifespan.
CLO 2: Analyze the pharmacodynamics and pharmacokinetic impact of pharmacologic therapies in the treatment of diseases and altered states.
CLO 3: Formulate therapeutic regimens for patients, including patients with altered pharmacodynamics and pharmacokinetics special populations, using cultural competence.
CLO 4: Evaluate the impact of pharmacogenomics, access, cost, quality, and safety on prescribing.

Step 1: View the CDC Module 1: Addressing the Opioid Epidemic.
Step 2: Review the CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016 (Note: This guideline is being updated).

After completing the steps above, proceed to the CDC MODULE QUIZ.

CDC Module Quiz

After viewing the CDC Module 1 and the CDC Guideline for Prescribing Opioids for Chronic Pain, please complete the 5-question quiz worth 50 points.

Respondus Practice Quiz – NUR 7560 (ungraded) (**Webcam**) – Requires Respondus LockDown Browser

The purpose of this Respondus Practice Quiz is multifactorial. It aims to:
– Check the functionality of the Respondus Lockdown Browser on your chosen device.
– Review course materials, including the syllabus, course schedule, and Week 1 information.

Unit 7: Neurologic Pharmacology

Welcome to Unit 7! This unit focuses on drugs that affect the central nervous system, which can be categorized into those used for psychiatric or neurological conditions. These drugs influence neuroreceptors and neurotransmitters in various parts of the brain to elicit specific responses. Understanding the central nervous system is crucial for rational drug selection and effective management of side effects.

Pain management, both acute and chronic, is a topic of national concern due to the high rates of controlled substance abuse. Treatment plans are guided by factors such as the pain’s history, intensity, duration, aggravating and relieving conditions, and the structures involved in causing the pain. In this course, we will delve into the pharmacology of pain management, focusing on treatment goals, rational drug selection, and ensuring a safe and effective treatment plan.

Unit Learning Objectives
1. Examine the principles of pathophysiology and therapeutics guiding pharmacotherapeutic interventions affecting the nervous system (CLO 1).
2. Analyze the pharmacokinetic and pharmacodynamic actions of agents affecting the nervous system (CLO 2).
3. Apply critical-thinking processes to manage and evaluate the expected effects, potential adverse effects, and potential interactions of pharmacological agents affecting the nervous system (CLO 3).
4. Apply critical-thinking processes to manage and evaluate the expected effects, potential adverse effects, and potential interactions of pharmacological agents affecting the nervous system (CLO 1, 2, 3).

Week 9/Unit 7 “To Do” List
– Complete the High-Yield Med Review Quiz by the end of Week 9.
– Complete the Shadow Health Focused Exam: Pain Management by the end of Week 9.
– Complete the Shadow Health Concept Lab: Analgesics by the end of Week 9.
– Prepare for the Unit 6 & 7 Exam in the following week.

Learning Materials

Lectures & E-Book
Busti, A. J. (2022). NP Curriculum Support-Advanced Pharmacology for NPs. MedEducation, LLC.
NEUROLOGIC PHARMACOLOGY
– Non-opioid Analgesics Review
– Opioid Analgesic Review
– Opioid Induced Side Effects
– Opioid Dose Equivalency
– Anticonvulsants Review Part 1
– Anticonvulsants Review Part 2
ADVANCED DRUG CLASS REVIEW TOPICS
– Alzheimer’s Disease
– Parkinson’s Disease

Optional Learning Resources:
Media
– Speed Pharmacology. Pharmacology – NSAIDs & prostaglandin analogs (made easy) [Video].
– Speed Pharmacology. Antiepileptic drugs (made easy) [Video].
– Speed Pharmacology. Opioids (made easy) [Video].

Websites
– Khan Academy. Nervous system diseases.
– University of Florida Health. Pain management and dosing guide.
– U.S. Department of Health and Human Services, Centers for Disease Control and Prevention. CDC guideline for prescribing opioids for chronic pain.
– U.S. Department of Health and Human Services, Centers for Disease Control and Prevention. Training for providers.
– U.S. Department of Health and Human Services, U.S. Food & Drug Administration. Training health care providers on pain management and safe use of opioid analgesics – Exploring the path forward.

HYMR Quiz – Neurology

After reviewing all assigned lectures and corresponding e-book chapters in High-Yield Med Review, complete the module quiz in the HYMR platform. This quiz consists of 10 questions and allows one attempt within 15 minutes. Your score will determine the corresponding points as follows:
– 100%: 20 points
– 90%: 18 points
– 80%: 16 points
– 70%: 14 points
– 60%: 12 points
– 50%: 10 points
– 40%: 8 points
– 30%: 6 points
– 20%: 4 points
– 10%: 2 points
– No submission: 0 points

Shadow Health: Concept Lab – Analgesics

The purpose of this Shadow Health Concept Lab assignment is to help you achieve the following Course Learning Outcomes 1-5.

Assignment:
This week, you will participate in a Shadow Health Concept Lab related to analgesic medications. This will provide you with insights into pharmacological concepts associated with commonly administered analgesic drugs. Completing this module should take approximately 30 minutes.

What to Submit:
Upon completion of the assignment, submit your completion certificate and a 1-page reflection response addressing the following question: How do you identify a patient that may be overusing or abusing prescription pain medications? How would you handle this concern if you are the NP seeing this patient?

Shadow Health: Focused Exam: Pain Management

The purpose of this Shadow Health Focused Exam assignment is to help you achieve Course Learning Outcomes 1-5.

Assignment:
This assignment involves conducting a focused exam on a patient with chronic pain, Tanner Bailey. You will use therapeutic communication techniques to obtain subjective data necessary for determining the appropriate pharmacological therapy for his condition. After the patient exam, you will select the medication best suited to Mr. Bailey’s needs and, if applicable, write a prescription for the selected medication. Please note that this assignment includes subjective data collection on sensitive topics like gender identity. This module should take approximately 90 minutes.

What

to Submit:
Upon completing the assignment, submit your completion certificate/lab pass showing your DCE score.

Unit Conclusion

As we conclude this week of advanced pharmacology, we have explored drugs that affect the central nervous system. These drugs play a critical role in the treatment of psychiatric and neurological conditions by influencing neuroreceptors and neurotransmitters in various brain regions.

Pain management, whether for acute or chronic pain, remains a topic of national concern due to the high rates of controlled substance abuse. Our study has focused on understanding the pharmacology of pain management, with an emphasis on treatment goals, rational drug selection, and ensuring safe and effective treatment plans. Keep this knowledge in mind as you progress in your studies.