

In this clinical scenario, we encounter Ms. Jones, a 67-year-old woman, who is accompanied by her daughter, Susan, for her office visit. Ms. Jones resides with her daughter and maintains her independence in performing activities of daily living (ADLs). Concerningly, her daughter reports a significant increase in her mother’s heart rate, accompanied by persistent coughing over the past two days.
Ms. Jones has a notable history of tobacco use, with a smoking history of 30 packs per year; however, she successfully quit smoking three years ago. Additionally, her medical history includes chronic obstructive pulmonary disease (COPD), hypertension, vitamin D deficiency, and hyperlipidemia. Furthermore, she reports intermittent pain and cramping in her lower extremities when walking, occasionally necessitating breaks for pain relief. She also experiences left-sided back pain and discomfort during aspiration.
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Ms. Jones acknowledges her recent and frequent bouts of coughing, accompanied by the production of thick, brown-tinged sputum. She attributes this to her COPD and an increased usage of her albuterol inhaler, which she finds helpful in loosening mucus. Although she describes a sense of fatigue and weakness, she still manages to fulfill her daily routine. Case Title: A 67-year-old With Tachycardia and Coughing
Vital Signs: Ms. Jones’ vital signs indicate a temperature of 99.2°F, blood pressure at 126/78 mm Hg, a heart rate of 96 beats per minute, and a respiratory rate of 22 breaths per minute.
Laboratory Results: A Complete Metabolic Panel and CBC were performed, and the results fell within the normal range.
Labs: Complete Metabolic Panel and CBC done and were within normal limits
CMP Component | Value | CBC Component | Value |
Glucose, Serum | 86 mg/dL | White blood cell count | 5.0 x 10E3/uL |
BUN | 17 mg/dL | RBC | 4.71 x10E6/uL |
Creatinine, Serum | 0.63 mg/dL | Hemoglobin | 10.9 g/dL |
EGFR | 120 mL/min | Hematocrit | 36.4% |
Sodium, Serum | 141 mmol/L | Mean Corpuscular Volume | 79 fL |
Potassium, Serum | 4.0 mmol/L | Mean Corpus HgB | 28.9 pg |
Chloride, Serum | 100 mmol/L | Mean Corpus HgB Conc | 32.5 g/dL |
Carbon Dioxide | 26 mmol/L | RBC Distribution Width | 12.3% |
Calcium | 8.7 mg/dL | Platelet Count | 178 x 10E3/uL |
Protein, Total, Serum | 6.0 g/dL | ||
Albumin | 4.8 g/dL | ||
Globulin | 2.4 g/dL | ||
Bilirubin | 1.0 mg/dL | ||
AST | 17 IU/L | ||
ALT | 15 IU/L |
Allergies: Penicillin
List of Current Medications:
– Atorvastatin 40mg orally once daily
– Multivitamin 1 tablet taken daily
– Losartan 50mg orally once daily
– ProAir HFA 90mcg: 2 puffs every 4-6 hours as needed
– Caltrate 600mg+ D3: 1 tablet daily
In this clinical scenario, we encounter Ms. Jones, a 67-year-old woman, who is accompanied by her daughter, Susan, for her office visit. Ms. Jones resides with her daughter and maintains her independence in performing activities of daily living (ADLs). Concerningly, her daughter reports a significant increase in her mother’s heart rate, accompanied by persistent coughing over the past two days.
Ms. Jones has a notable history of tobacco use, with a smoking history of 30 packs per year; however, she successfully quit smoking three years ago. Additionally, her medical history includes chronic obstructive pulmonary disease (COPD), hypertension, vitamin D deficiency, and hyperlipidemia. Furthermore, she reports intermittent pain and cramping in her lower extremities when walking, occasionally necessitating breaks for pain relief. She also experiences left-sided back pain and discomfort during aspiration.
Ms. Jones acknowledges her recent and frequent bouts of coughing, accompanied by the production of thick, brown-tinged sputum. She attributes this to her COPD and an increased usage of her albuterol inhaler, which she finds helpful in loosening mucus. Although she describes a sense of fatigue and weakness, she still manages to fulfill her daily routine.
Vital Signs:
Ms. Jones’ vital signs indicate a temperature of 99.2°F, blood pressure at 126/78 mm Hg, a heart rate of 96 beats per minute, and a respiratory rate of 22 breaths per minute.
Laboratory Results:
A Complete Metabolic Panel and CBC were performed, and the results fell within the normal range.
Now, let’s proceed to answer the provided questions:
Chest X-ray results may reveal the presence of white infiltrates in the lungs, which can be indicative of infection and help confirm the diagnosis of pneumonia.
Ms. Jones is diagnosed with community-acquired pneumonia (CAP). CAP is contracted outside of a clinical environment, and in this case, Ms. Jones did not acquire the illness from a healthcare facility.
The CURB-65 calculator is a valuable tool to assess the severity of community-acquired pneumonia. It considers factors like confusion, uremia, respiratory rate, blood pressure, and age over 65 (CURB-65). Based on Ms. Jones’ clinical presentation, she scores 1 on the CURB-65 scale, suggesting outpatient treatment.
Ms. Jones’ CURB-65 score is calculated as follows: she is not confused, her BUN level is 17 mg/dl, her respiratory rate is 22, her systolic pressure is 126, and she is 67 years old. With a score of 1, outpatient treatment is recommended.
Given her penicillin allergy and the nature of her condition, I recommend a treatment regimen consisting of Levofloxacin 750 mg orally once daily for five days. Additionally, considering her intermittent leg pain, prescribing 100 mg of cilostazol orally twice a day would be appropriate.
The gold standard for measuring airflow limitation in COPD is spirometry. It is crucial to confirm COPD and determine the appropriate treatment plan.
Intermittent claudication is a potential diagnosis based on the intermittent leg pain and cramping experienced by Ms. Jones. This condition often results from peripheral artery disease, causing pain during exertion that subsides with rest.
To further evaluate Ms. Jones’ intermittent leg pain, an Ankle-Brachial Index (ABI) test could be ordered. This test compares blood pressure measurements in the arm and ankle and can detect arterial blockages or obstructions.
Three differentials for Ms. Jones’ initial presentation could include COPD exacerbation, Cardiogenic Pulmonary Edema, and Influenza.
Patient education should include information on the increased risk of pneumonia in unvaccinated individuals, particularly those with underlying conditions like hypertension and COPD. Ms. Jones should be advised to stay hydrated, perform frequent coughing, and engage in deep breathing exercises.
A follow-up appointment within two to three weeks is recommended. Ms. Jones should be instructed to contact a healthcare provider if her cough worsens or if her leg pain persists.
Amoxicillin/clavulanate plus a macrolide could have been an option to treat Ms. Jones’ pneumonia, considering her penicillin allergy. This combination is effective in enhancing mucociliary clearance and reducing the inflammatory response, potentially leading to improved health outcomes.
References
Global Initiative for Chronic Obstructive Lung Disease. (2020). GOLD spirometry guide. https://goldcopd.org/gold-spirometry-guide/
Herraiz-Adillo, Á., Cavero-Redondo, I., Álvarez-Bueno, C., Pozuelo-Carrascosa, D. P., & Solera-Martínez, M. (2020). The accuracy of toe brachial index and ankle brachial index in the diagnosis of lower limb peripheral arterial disease: A systematic review and meta-analysis. Atherosclerosis, 315, 81-92. https://doi.org/10.1016/j.atherosclerosis.2020.09.026
Ilg, A., Moskowitz, A., Konanki, V., Patel, P., Chase, M., Grossestreuer, A., & Donnino, M. (2018). 1054: Performance of curb-65 in predicting critical care interventions in patients with pneumonia. Critical Care Medicine, 46(1), 511-511. https://doi.org/10.1097/01.ccm.0000529060.29903.34
Ito, A., Ishida, T., Tachibana, H., Tokumasu, H., Yamazaki, A., & Washio, Y. (2019). Azithromycin combination therapy for community-acquired pneumonia: propensity score analysis. Scientific Report, 9(18406). https://doi.org/10.1038/s41598-019-54922-4
Patel, S. K., & Surowiec, S. M. (2021). Intermittent claudication. In StatPearls [Internet]. StatPearls Publishing. Case Title: A 67-year-old With Tachycardia and Coughing
Poovieng, J., Sakboonyarat, B., & Nasomsong, W. (2022). Bacterial etiology and mortality rate in community-acquired pneumonia, healthcare-associated pneumonia and hospital-acquired pneumonia in Thai university hospital. Scientific Reports, 12(1). https://doi.org/10.1038/s41598-022-12904-z
Seo, W. J., Kang, J., Kang, H. K., Park, S. H., Koo, H., Park, H. K., Lee, S., Song, J. E., Kwak, Y. G., & Kang, J. (2022). Impact of prior vaccination on clinical outcomes of patients with COVID-19. Emerging Microbes & Infections, 11(1), 1316-1324. https://doi.org/10.1080/22221751.2022.2069516 Case Title: A 67-year-old With Tachycardia and Coughing
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