Unit 8: Gastrointestinal Pharmacology
There is a diverse range of medications utilized in the management of gastrointestinal disorders. Certain categories of drugs are primarily designated for the treatment of GI conditions. In this unit, our focus will be on primary care, and we will not delve into intravenous formulations. Our emphasis remains on understanding clinical use, dosing, rational drug selection, and patient education, much like in previous units.
Primary care practitioners frequently encounter a variety of GI disorders, including gastroesophageal reflux disease and peptic ulcer disease. Over-the-counter medications have become increasingly available for treating these conditions in recent years. Nevertheless, it is essential to grasp the underlying pathophysiology and recognize instances when over-the-counter treatments are ineffective. We will also explore stepwise approaches to care and considerations for special populations.
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Career Goals: Strengths and Challenges Related to Nursing Practice Competencies
Unit Learning Objectives
1. Scrutinize the principles of pathophysiology and therapeutics guiding pharmacotherapeutic interventions affecting the gastrointestinal system.
2. Analyze the pharmacokinetic and pharmacodynamic actions of agents influencing the gastrointestinal system.
3. Apply critical-thinking processes to manage and assess the expected effects, potential adverse effects, and interactions of pharmacological agents impacting the gastrointestinal system.
4. Implement evidence-based pharmacotherapeutic interventions for patients with gastrointestinal system disorders.
5. Assess the influence of pharmacogenomics, access, cost, quality, and safety on prescribing drugs affecting the Gastrointestinal System.
Week 10/Unit 8 “To Do” List
– Complete High-Yield Med Review Quiz by Sunday Week 10
– Unit 6 & 7 Exam available Thursday 11/10 to Saturday 11/12 (Access via Respondus)
Learning Materials
Learning Materials
Lectures & E-Book
Busti, A. J. (2022). NP Curriculum Support-Advanced Pharmacology for NPs. MedEducation, LLC.
GASTROINTESTINAL PHARMACOLOGY
– 5-ASA Derivatives
– Antacids
– Antidiarrheals
– Antiemetics
– Fiber, laxatives, Stool Softeners
SPECIAL TOPICS IN PHARMACOLOGY
– Drug Food Interactions
– Drug Gastric Acid Interactions
Optional Learning Resources:
Media
Parkes, C. (2019a, June 26). Nursing pharmacology – H2 receptor antagonists, PPIs, sucralfate, antacids, prostaglandins [Video]. YouTube. https://www.youtube.com/watch?v=tYnSDaHQNhM
Parkes, C. (2019b, June 26). Nursing pharmacology – antiemetic, antidiarrhea medications and prokinetic agents [Video]. YouTube. https://www.youtube.com/watch?v=vmbfLsNbMpk
Websites
Khan Academy. (2018a). Advanced gastrointestinal physiology. Retrieved March 11, 2021, from https://www.khanacademy.org/science/health-and-medicine/gastro-intestinal-system
Khan Academy. (2018c). Gastrointestinal system diseases. Retrieved March 11, 2021, from https://www.khanacademy.org/science/health-and-medicine/gastrointestinal-system-diseases
HYMR Quiz – GI
Following review of all assigned lectures and correlating E-book chapters in High Yield Med Review, you will complete the module quiz in the HYMR platform.
– From the Dashboard select “EXAMS”
– Navigate to the “GI-Self Assessment”
– Click “Take Exam”
You will have one attempt to complete 5 questions in 10 minutes. Once completed, please take a screen shot of your score and upload to this assignment tab for grading. This quiz is worth 20 points, so based on your % score you will receive the correlating points below.
– 100% 20 points
– 90% 18 points
– 80% 16 points
– 70% 14 points
– 60% 12 points
– 50% 10 points
– 40% 8 points
– 30% 6 points
– 20% 4 points
– 10% 2 points
– No submission 0 points
*Please note, faculty are able to view your time and activity in HYMR.*
Unit Conclusion
Unit Conclusion
As we conclude unit 8 of Advanced Pharmacology, we have explored the extensive array of medications employed in the treatment of gastrointestinal disorders. Our study has delved into the in-depth management of GI disorders. It is crucial to bear in mind stepwise approaches to care and considerations for special populations when prescribing medications. Remember that rational drug selection involves focusing on resolving or treating the underlying disease state while minimizing side effects.
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Gastrointestinal Pharmacology
Welcome to Unit 8 of Advanced Pharmacology
There are a wide variety of drugs used to treat gastrointestinal disorders. Several groups of drugs are used almost exclusively to treat GI conditions. Our focus will be primary care thus intravenous formulations will not be discussed. Clinical use and dosing of drugs will be the focus as with other units and include an emphasis on rational drug selection and patient education in nursing.Primary care providers also see a variety of GI disorders, including gastroesophageal reflux disease and peptic ulcer disease. Over the past several years, over-the-counter medications have become available to treat these conditions. However, it is important to understand the underlying pathophysiology, and know when over-the-counter treatment is ineffective. Stepwise approaches to care and special population considerations will be discussed.Unit Learning Objectives
- Examine the principles of pathophysiology and therapeutics that direct the pharmacotherapeutic interventions affecting the gastrointestinal system (CLO 1)
- Analyze the pharmacokinetic and pharmacodynamic actions of agents affecting the gastrointestinal system (CLO 2)
- Apply critical-thinking processes to the management and evaluation of expected effects, potential adverse effects, and potential interactions of pharmacological agents affecting the gastrointestinal system (CLO 1,2)
- Apply the evidence for pharmacotherapeutic interventions in a patient with gastrointestinal system disorders (CLO 1,2,3)
- Evaluate the impact of pharmacogenomics, access, cost, quality, and safety on prescribing for Drugs Affecting the Gastrointestinal System (CLO 4)
Week 10/Unit 8 “To Do” List- Complete High-Yield Med Review Quiz by Sunday Week 10
- Unit 6 & 7 Exam available Thursday 11/10 to Saturday 11/12 (Access via Respondus)
-
Learning Materials
Lectures & E-Book- Busti, A. J. (2022). NP Curriculum Support-Advanced Pharmacology for NPs. MedEducation, LLC.
- GASTROINTESTINAL PHARMACOLOGY
- 5-ASA Derivatives
- Antacids
- Antidiarrheals
- Antiemetics
- Fiber, laxatives, Stool Softeners
- SPECIAL TOPICS IN PHARMACOLOGY
- Drug Food Interactions
- Drug Gastric Acid Interactions
- GASTROINTESTINAL PHARMACOLOGY
Optional Learning Resources:Media- Parkes, C. (2019a, June 26). Nursing pharmacology – H2 receptor antagonists, PPIs, sucralfate, antacids, prostaglandins [Video]. YouTube. https://www.youtube.com/watch?v=tYnSDaHQNhM
- Parkes, C. (2019b, June 26). Nursing pharmacology – antiemetic, antidiarrhea medications and prokinetic agents [Video]. YouTube. https://www.youtube.com/watch?v=vmbfLsNbMpk
Websites- Khan Academy. (2018a). Advanced gastrointestinal physiology. Retrieved March 11, 2021, from https://www.khanacademy.org/science/health-and-medicine/gastro-intestinal-system
- Khan Academy. (2018c). Gastrointestinal system diseases. Retrieved March 11, 2021, from https://www.khanacademy.org/science/health-and-medicine/gastrointestinal-system-diseases
- Busti, A. J. (2022). NP Curriculum Support-Advanced Pharmacology for NPs. MedEducation, LLC.
-
Following review of all assigned lectures and correlating E-book chapters in High Yield Med Review, you will complete the module quiz in the HYMR platform.
- From the Dashboard select “EXAMS”
- Navigate to the “GI-Self Assessment”
- Click “Take Exam”
You will have one attempt to complete 5 questions in 10 minutes. Once completed, please take a screen shot of your score and upload to this assignment tab for grading. This quiz is worth 20 points, so based on your % score you will receive the correlating points below.100% 20 points 90% 18 points 80% 16 points 70% 14 points 60% 12 points 50% 10 points 40% 8 points 30% 6 points 20% 4 points 10% 2 points No submission 0 points *Please note, faculty are able to view your time and activity in HYMR.* -
Unit Conclusion
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As we wrap up unit 8 of Advanced Pharmacology, we discussed the wide variety of drugs used to treat gastrointestinal disorders. We also learned in-depth treatment of GI disorders. Stepwise approaches to care and special population considerations are always important to remember when prescribing medications. Recall that rational drug selection emphasizes concentrating on resolving or treating the underlying disease state while reducing side effects.